Cognition in ALS: a 20-Year Journey

Invited speaker: Dr. Michael J. Strong, MD, FRPC(C), FAAN, FCAHS, Western University, London, Ontario.

Dr. Michael Strong is Dean of the Schulich School of Medicine & Dentistry, a Distinguished University Professor at Western University, and the Arthur J. Hudson Chair in ALS Research.  He graduated from Queens University in Kingston in 1982 followed by Neurology training at the Western University (1982 – 1987) and post graduate training at the Laboratory of Central Nervous System Studies (director – D. Carleton Gadjusek, Nobel Laureate) at the National Institutes of Health.

His research has focused on understanding how neurofilament aggregates are formed in degenerating motor neurons in ALS and how these contribute to the disease process of ALS.  These studies have led to the current hypothesis that ALS is due, in the majority of cases, from fundamental alterations in RNA metabolism. In addition, both his clinical and laboratory research have focused on understanding the nature of cognitive changes in ALS, ultimately leading to the demonstration that cognitive changes in ALS are associated with alterations in the tau protein metabolism.